PSF
•Publications•
2006
Babu A. Manjasetty, Konrad Büssow, Martin Fieber-Erdmann, Yvette Roske, Johan Gobom, Christoph Scheich, Frank Götz, Frank H. Niesen and Udo Heinemann
Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold
Protein Science 2006, in press
2005
Babu A Manjasetty, Frank H Niesen, Christoph Scheich, Yvette Roske, Frank Götz,
Joachim Behlke, Volker Sievert, Udo Heinemann and Konrad Büssow
X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1)
BMC Structural Biology 2005, 5:21.
Konrad Büssow, Christoph Scheich, Volker Sievert, Ullrich Harttig, Jörg Schultz, Bernd Simon, Peer Bork, Hans Lehrach, Udo Heinemann
Structural Genomics of human proteins - target selection and generation of a public catalog of expression clones
Microbial Cell Factories 2005, 4:21.
Daniel Kümmel, Jürgen J. Müller, Yvette Roske, Rolf Misselwitz, Konrad Büssow, Udo Heinemann
The structure of the TRAPP subunit TPC6 suggests a model for a TRAPP subcomplex
EMBO reports 2005, 6(8):787.793
Andrew P. Turnbull, Daniel Kümmel, Bianka Prinz, Caterina Holz,
Jeffrey Schultchen, Christine Lang, Frank H. Niesen, Klaus-Peter Hofmann,
Heinrich Delbrück, Joachim Behlke, Eva-Christina Müller,
Ernst Jarosch, Thomas Sommer and Udo Heinemann
Structure of palmitoylated BET3:
insights into TRAPP complex assembly and membrane localization.
EMBO Journal 2005, 24(5):875-84.
2004
Michael Soukenik, Anne Diehl, Martina Leidert, Volker Sievert, Konrad Büssow,
Dietmar Leitner, Dirk Labudde, Linda J. Ball, Annette Lechner, Dorit K. Nägler, Hartmut Oschkinat
The SEP domain of p47 acts as a reversible competitive inhibitor of cathepsin L.
FEBS Letters 2004, 576(3):358-362.
Babu A Manjasetty, Frank H Niesen, Heinrich Delbrück, Frank Götz, Volker Sievert, Konrad Büssow, Joachim Behlke and Udo Heinemann
X-ray structure of Fumarylacetoacetate Hydrolase(FAH) family member Homo sapiens FLJ36880.
Biological Chemistry 2004, 385(10):935-942.
Catherina Holz and Christine Lang
High-throughput expression in microplate format in Saccharomyces cerevisiae
Methods in Molecular Biology 2004, 267:267-276.
Mewes Böttner and Christine Lang
High-throughput expression in microplate format in Pichia pastoris
Methods in Molecular Biology 2004, 267:277-286.
Konrad Büssow, Claudia Quedenau, Volker Sievert, Janett Tischer, Christoph Scheich,
Harald Seitz, Brigitte Hieke, Frank H. Niesen, Frank Götz, Ulrich Harttig and Hans Lehrach
A catalogue of human cDNA expression clones and its application to structural genomics.
Genome Biology 2004, 5:R71.
Bianka Prinz, Jeffrey Schultchen, Ralf Rydzewski, Caterina Holz, Mewes Boettner, Ulf Stahl and Christine Lang
Establishing a versatile fermentation and purification procedure for human proteins expressed in the yeasts Saccharomyces cerevisiae and Pichia pastoris for structural genomics
Journal of Structural and Functional Genomics 2004, 5: 29-44
Christoph Scheich, Dietmar Leitner, Volker Sievert, Martina Leidert,
Brigitte Schlegel, Bernd Simon, Ivica Letunic, Konrad Büssow
and Anne Diehl
Fast identification of folded human protein domains
expressed in E. coli suitable for structural analysis
BMC Structural Biology 2004, 4:4
Babu A. Manjasetty, Claudia Quedenau, Volker Sievert, Konrad Büssow, Frank Niesen, Heinrich
Delbrück, Udo Heinemann
X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma
Proteins: Structure, Function, and Bioinformatics 2004, 55(1):214-217
Christoph Brockmann,
Dietmar Leitner,
Dirk Labudde,
Anne Diehl,
Volker Sievert,
Konrad Büssow,
Ronald Kühne and
Hartmut Oschkinat
The solution structure of the SODD BAG domain reveals additional electrostatic
interactions in the HSP70 complexes of SODD subfamily BAG domains
FEBS Letters 2004 558(1-3):101-106
Babu A Manjasetty, Heinrich Delbrück, Dinh Trung Pham, Uwe Mueller, Martin
Fieber-Erdmann, Christoph Scheich, Volker Sievert, Konrad Büssow,
Frank Niesen, Wilhelm Weihofen, Bernhard Loll, Wolfram Saenger and Udo
Heinemann
Crystal structure of Homo sapiens protein hp14.5.
Proteins: Structure, Function and Bioinformatics 2004, 54: 797-800
Uwe Mueller, Konrad Büssow, Anne Diehl, Franz J. Bartl, Frank H. Niesen, Lajos Nyarsik and
Udo Heinemann
Rapid purification and crystal structure analysis of a small protein
carrying two terminal affinity tags.
Journal of Structural and Functional Genomics 2004, 4: 217-225
Christoph Scheich, Frank Niesen, Robert Seckler and Konrad Büssow
An automated in vitro protein folding screen applied to a human dynactin
subunit
Protein Science 2004, 13: 370-380
2003
Christoph Scheich, Volker Sievert and Konrad Büssow
An automated method
for high-throughput protein purification applied to a comparison of His-tag
and GST-tag affinity chromatography
BMC Biotechology 2003, 3:12
Caterina Holz, Bianka Prinz, Natalia Bolotina, Volker Sievert, Konrad Büssow,
Bernd Simon, Ulf Stahl and Christine Lang
Establishing
the yeast Saccharomyces cerevisiae as a system for expression of human
proteins on a proteome-scale
Journal of Structural and Functional Genomics, 4(2-3): 97-108
Babu A Manjasetty, Klaus Höppener, Uwe Mueller and Udo Heinemann
Secure web book to
store the structural genomics research data.
Journal of Structural and Functional Genomics,4(2-3): 121-127
Udo Heinemann, Konrad Büssow, Uwe Mueller, and Patrick Umbach
Facilities and methods for the high-throughput crystal structure analysis
of human proteins
Accounts of Chemical Research 2003, 36(3):157-16
2002
Mewes Boettner, Bianca Prinz, Caterina Holz, Ulf Stahl, Christine Lang
High-throughput
screening for expression of heterologous proteins in the yeast Pichia
pastoris.
Journal of Biotechnology 2002, 99(1):51-62
Caterina Holz, Oliver Hesse, Natalia Bolotina, Ulf Stahl, Christine Lang
A micro-scale
process for high-throughput expression of cDNAs in the yeast Saccharomyces
cerevisiae.
Protein Expression & Purification 2002, 25(3):372-378
Konrad Büssow, Steve Hoffmann and Volker Sievert
ORFer - retrieval
of protein sequences and open reading frames from GenBank and storage
into relational databases or text files
BMC Bioinformatics 2002, 3:40
Udo Heinemann
Establishing a structural genomics platform: The Berlin-based Protein
Structure Factory.
Gene Funct. Dis. 2002, 3:25-32.
2001
Udo Heinemann, Gerd Illing, Helmut Oschkinat
High-throughput
three-dimensional protein structure determination.
Current Opinion in Biotechnology 2001, 12(4):348-354
Udo Heinemann, Juergen Frevert, Klaus-Peter Hofmann, Gerd Illing, Hartmut
Oschkinat, Wolfram Saenger and Rolf Zettl
The Berlin "Protein Structure Factory"
initiative (text available on this web site)
Uwe Mueller, Lajos Nyarsik, Martin Horn, Holger Rauth, Thomas Przewieslik,
Wolfram Saenger, Hans Lehrach and Holger Eickhoff
Development
of a technology for automation and miniaturization of protein crystallization.
Journal of Biotechnology 2001, 85:7-14
Udo Heinemann
The Berlin "Protein Structure Factory" initiative: A technology-oriented
approach to structural genomics. In:"Data Mining in Structural Biology:
Signal Transduction and Beyond" (Schlichting, I. & Egner, U., eds) Springer,
Berlin, Heidelberg, New York, pp. 101-121
Patrick Umbach and Udo Heinemann
Die Proteinstrukturfabrik- Strukturanalyse mit hohem Durchsatz im Berliner
Forschungsverbund. BioSpektrum 2001, 7:247-249.
2000
Udo Heinemann
Structural
genomics in Europe: Slow start, strong finish?
Nature Structural Biology 2000, 7(Suppl S):940-942
Udo Heinemann, Juergen Frevert, Klaus-Peter Hofmann, Gerd Illing, Cornelia
Maurer, Hartmut Oschkinat and Wolfram Saenger
An integrated
approach to structural genomics.
Progress in Biophysics & Molecular Biology 2000, 73:347-362
Heinemann, U., Frevert, J., Hofmann, K.-P., Illing, G., Oschkinat, H., Saenger, W. & Zettl, R. (2000) Linking structural biology with genome research: The Berlin "Protein Structure Factory" initiative. In:"Genomics and Proteomics - Functional and Computational Aspects" (Suhai, S. ed.) Kluwer Academic / Plenum, New York, pp. 179-189.
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© 2003 PSF, last changed 22 Feb 2006